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Plasma FGF21 concentrations and spontaneous self-selection of protein suggest that 15% protein in the diet may not be enough for male adult rats

Abstract : Under dietary self-selection, rats choose to ingest 25%–30% of energy as protein, a value higher than the protein requirement (10%–15%). According to our results, this higher spontaneous intake reflects the fact that rats fed a 15% protein diet, compared with high-protein diets, tend to bind more fat and have higher concentrations of FGF21, a hormone signaling protein deficiency. A 15% protein diet appears to be sufficient for protein homeostasis but not for optimal energy homeostasis.
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https://hal-agroparistech.archives-ouvertes.fr/hal-03810602
Contributor : Dalila Azzout-Marniche Connect in order to contact the contributor
Submitted on : Tuesday, October 11, 2022 - 3:07:39 PM
Last modification on : Saturday, October 22, 2022 - 4:43:58 AM

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Josephine Gehring, Dalila Azzout-Marniche, Catherine Chaumontet, Claire Gaudichon, Patrick Even. Plasma FGF21 concentrations and spontaneous self-selection of protein suggest that 15% protein in the diet may not be enough for male adult rats. AJP - Endocrinology and Metabolism, 2022, 322 (2), pp.E154-E164. ⟨10.1152/ajpendo.00204.2021⟩. ⟨hal-03810602⟩

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