AgroParisTech (16 rue Claude Bernard F-75231 Paris Cedex 05 - France)
Abstract : The common chemical method to synthesize Phenolic Acids (PAs) involves a relatively considerable energy intake. In order to solve this issue, microwave-assisted Knoevenagel-Doebner condensations were developed. Nevertheless, these synthetic procedures prove difficult to reproduce. Herein, we developed and optimized-by using a combination of a Design of Experiment and a standard optimization approach-a reliable procedure that converts naturally occuring p-hydroxybenzaldehydes into the corresponding PAs with conversions of 86-99% and in 85-97% yields.
https://hal-agroparistech.archives-ouvertes.fr/hal-02527502
Contributor : Louis Mouterde <>
Submitted on : Wednesday, April 1, 2020 - 11:21:58 AM Last modification on : Monday, April 6, 2020 - 3:27:25 PM