VARIABLE SELECTION IN SPARSE MULTIVARIATE GLARMA MODELS: APPLICATION TO GERMINATION CONTROL BY ENVIRONMENT

M Gomtsyan (1) , Céline Lévy-Leduc (1) , Sarah Ouadah (1) , Laure Sansonnet (1) , C Bailly (2) , Loïc Rajjou (3)

1 MIA Paris-Saclay - Mathématiques et Informatique Appliquées
2 LBD - Laboratoire de Biologie du Développement [IBPS]
3 IJPB - Institut Jean-Pierre Bourgin

We propose a novel and efficient iterative two-stage variable selection approach for multivariate sparse GLARMA models, which can be used for modelling multivariate discrete-valued time series. Our approach consists in iteratively combining two steps: the estimation of the autoregressive moving average (ARMA) coefficients of multivariate GLARMA models and the variable selection in the coefficients of the Generalized Linear Model (GLM) part of the model performed by regularized methods. We explain how to implement our approach efficiently. Then we assess the performance of our methodology using synthetic data and compare it with alternative methods. Finally, we illustrate it on RNA-Seq data resulting from polyribosome profiling to determine translational status for all mRNAs in germinating seeds. Our approach, which is implemented in the MultiGlarmaVarSel R package and available on the CRAN, is very attractive since it benefits from a low computational load and is able to outperform the other methods for recovering the null and non-null coefficients.

Mots clés: multivariate GLARMA; sparsity; variable selection; seed quality; gene expression

Domaines: Statistiques [stat]

M Gomtsyan, Céline Lévy-Leduc, Sarah Ouadah, Laure Sansonnet, C Bailly, et al.. VARIABLE SELECTION IN SPARSE MULTIVARIATE GLARMA MODELS: APPLICATION TO GERMINATION CONTROL BY ENVIRONMENT. 2022. ⟨hal-03905876⟩