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Journal Articles Molecules Year : 2020

Innovative Bio-Based Organic UV-A and Blue Light Filters from Meldrum’s Acid

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Cédric Peyrot
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Matthieu Mention
Fanny Brunissen
Florent Allais

Abstract

Faced with the ban of some organic UV filters such as octinoxate or avobenzone, especially in Hawaii, it became essential to offer new alternatives that are both renewable and safe for humans and the environment. In this context, a class of bio-based molecules displaying interesting UV filter properties and great (photo)stability has been developed from Meldrum's acid and bio-based and synthetic p-hydroxycinnamic acids, furans and pyrroles. Moreover, p-hydroxycinnamic acid-based Meldrum's derivatives possess valuable secondary activities sought by the cosmetic industry such as antioxidant and anti-tyrosinase properties. The evaluation of the properties of mixture of judiciously chosen Meldrum's acid derivatives highlighted the possibility to modulate secondary activity while maintaining excellent UV protection. Meldrum's acid derivatives are not only competitive when benchmarked against organic filters currently on the market (i.e., avobenzone), but they also do not exhibit any endocrine disruption activity.
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Dates and versions

hal-03630941 , version 1 (05-04-2022)

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Cédric Peyrot, Matthieu Mention, Fanny Brunissen, Patrick Balaguer, Florent Allais. Innovative Bio-Based Organic UV-A and Blue Light Filters from Meldrum’s Acid. Molecules, 2020, 25 (9), pp.2178. ⟨10.3390/molecules25092178⟩. ⟨hal-03630941⟩
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