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Review: Use and misuse of meta-analysis in Animal Science

Abstract : In animal sciences, the number of published meta-analyses is increasing at a rate of 15% per year. This current review focuses on the good practices and the potential pitfalls in the conduct of meta-analyses in animal sciences, nutrition in particular. Once the study objectives have been defined, several key phases must be considered when doing a meta-analysis. First, as a principle of traceability, criteria used to select or discard publications should be clearly stated in a way that one could reproduce the final selection of data. Then, the coding phase, aiming to isolate specific experimental factors for an accurate graphical and statistical interpretation of the database, is discussed. Following this step, the study of the levels of independence of factors and of the degree of data balance of the meta-design represents an essential phase to ensure the validity of statistical processing. The consideration of the study effect as fixed or random must next be considered. It appears based on several examples that this choice does not generally have any influence on the conclusions of a meta-analysis when the number of experiments is sufficient.
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https://hal-agroparistech.archives-ouvertes.fr/hal-03016921
Contributor : Christelle Loncke <>
Submitted on : Friday, November 20, 2020 - 4:05:36 PM
Last modification on : Thursday, August 5, 2021 - 3:49:21 AM

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Daniel Sauvant, M. Letourneau-Montminy, Philippe Schmidely, Maryline Boval, Christelle Loncke, et al.. Review: Use and misuse of meta-analysis in Animal Science. animal, Published by Elsevier (since 2021) / Cambridge University Press (until 2020), 2020, 14 (S2), pp.s207-s222. ⟨10.1017/s1751731120001688⟩. ⟨hal-03016921⟩

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