Oleic acid accumulating Camelina produced by CRISPR-Cas9 gene editing

Morineau Céline 1 Bellec Yannick 1 Frédérique Tellier 1 Lionel Gissot 1 Zoltan Kelemen 1 Fabien Nogué 1 Jean-Denis Faure 1
1 IJPB - Institut Jean-Pierre Bourgin
Abstract : The possibility of selectively engineering gene dosage, particularly in polyploid genomes, would provide an efficient tool for plant breeding. The hexaploid oilseed crop Camelina sativa, which has three closely-related expressed sub-genomes, is an ideal species for the creation of a large collection of combinatorial mutants. Selective, targeted mutagenesis of the three delta-12-desaturase (FAD2) genes was achieved by CRISPR-Cas9 gene editing, leading to reduced levels of polyunsaturated fatty acids and increased accumulation of oleic acid in the oil (Morineau et al. in press).
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Conference papers
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https://hal-agroparistech.archives-ouvertes.fr/hal-01529211
Contributor : Jean-Denis Faure <>
Submitted on : Tuesday, May 30, 2017 - 4:02:58 PM
Last modification on : Thursday, February 28, 2019 - 5:45:06 PM

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AGROPARISTECH | INRA | UNIV-PARIS-SACLAY

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Morineau Céline, Bellec Yannick, Frédérique Tellier, Lionel Gissot, Zoltan Kelemen, et al.. Oleic acid accumulating Camelina produced by CRISPR-Cas9 gene editing . Gordon Conference on Plant Lipids, Jan 2017, Galveston, TX, United States. 〈https://www.grc.org/programs.aspx?id=13966〉. 〈hal-01529211〉

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