Expression Cell model RNA splicing Dystrophin Genotype phenotype correlation Myotonic dystrophy Cell penetrating peptide PCR Cardiac muscle Thérapie génique CONGENITAL MYATHENIC SYNDROME Cytoskeleton Gene therapy Trinucleotide Repeat Expansion Myotonic Dystrophy type 1 CTG repeat instability Oligodendrocyte ARN RNA interference Glial cells Transgenic mouse model Trinucleotide repeat expansion Mouse model MBNL CTG repeat contractions Lc3 Gene editing Myotonic dystrophy mouse models Mice Acetylcholinesterase knockout mouse Alternative splicing Quantitative microdialysis Brain Animals CRISPR/Cas9 Central nervous system Intermediate filament GABA Myotonic Dystrophy Cell culture model Long read sequencing Autophagy Muscular dystrophy CMS Desmin AAV Duchenne muscular dystrophy Mouse models Antisense oligonucleotide Exercise Centronuclear myopathy Therapy Humans Dilated cardiomyopathy BIOLOGIE MOLECULAIRE RNA biology GSK3␤ Astrocytes DM1 CTG repeats Heart Hypoxia Dystrophie Myotonique Antisense oligonucleotides Muscle Exercice Glucocorticoid-receptor Motoneuron Acute coronary syndrome Glutamate Acetylcholinesterase deficiency Glucocorticoids CRISPRi Dynamin 2 Oligodendrocytes ACETYLCHOLINESTERASE Skeletal muscle Maximal force Male DMSXL mice Aging Heart failure Dystrophie myotonique Transgenic mouse In vivo Diaphragm Myostatin Knockout Myotonic dystrophy type 1 Fibrosis Gene Therapy DMPK Myelin Neuron KNOCKOUT MICE Astrocyte Brain dysfunction Transcriptomics PacBio Myotonic Dystrophy Type 1