Patient specific tracts-based analysis of diffusion compartment models: application to multiple sclerosis patients with acute optic neuritis - INRIA - Institut National de Recherche en Informatique et en Automatique Accéder directement au contenu
Communication Dans Un Congrès Année : 2021

Patient specific tracts-based analysis of diffusion compartment models: application to multiple sclerosis patients with acute optic neuritis

Résumé

Multiple sclerosis is a complex disease where voxel-based, group-based statistics of the brain microstructure have shown their limits in explaining patient evolution. This is first due to too simple diffusion models, mixing information. Voxel-based studies also lack knowledge on brain structural connectivity. Finally, group-based analysis does not describe well the specific patient status (a crucial point for clinicians). We propose an atlas-based framework, combined with advanced diffusion compartment models, for patient specific analysis of microstructural disease burden on major fiber bundles. We apply our framework to the analysis of optic radiations of MS patients with acute optic neuritis.
Fichier principal
Vignette du fichier
ISMRM_2021.pdf (7.47 Mo) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)

Dates et versions

hal-03202059 , version 1 (19-04-2021)

Identifiants

  • HAL Id : hal-03202059 , version 1

Citer

Olivier Commowick, Renaud Hédouin, Charlotte Laurent, Jean-Christophe Ferré. Patient specific tracts-based analysis of diffusion compartment models: application to multiple sclerosis patients with acute optic neuritis. ISMRM 2021 - International Society for Magnetic Resonance in Medicine, May 2021, Toronto, Canada. pp.1-6. ⟨hal-03202059⟩
104 Consultations
91 Téléchargements

Partager

Gmail Facebook X LinkedIn More